TLR1- cluster of differentiation 281

acne, Health care, And Treatment Related Article! ― Toll-like receptor 1 (TLR1) often designated as CD281 (cluster of differentiation 281), a member of the Toll-like receptor family recognizes pathogen-associated molecular pattern with specificity for gram-positive bacteria. TLR1 is a 786-residue type I transmembrane protein with a 581-amino acid leucine-rich extracellular domain (ECD), a 23-amino acid transmembrane domain (amino acids 582 to 604), and a 181-amino acid cytoplasmic Toll homology signalling domain (1, 2). TLR1 maps to chromosome[...]