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Med-Chemist

 Med-Chemist ― http://www.med-chemist.com

I do blog on recent developments in drug discovery, spectroscopy, synthetic organic chemistry, FDA approvals, clinical trials. Also covers on natural products of pharmacological/biological importance.

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Listed: Feb 28, 2010

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FDA Approves Tafinlar (dabrafenib) for Advanced Melanoma

FDA Approves Tafinlar (dabrafenib) for Advanced Melanoma

Med-Chemist ― In conyinaution of my update on Dabrafenib ∙ GlaxoSmithKline plc announced today that the U.S. Food and Drug Administration (FDA) has approved Tafinlar (dabrafenib). Tafinlar is indicated as a single-agent oral treatment for unresectable...

Tags: Dabrafenib, Tafinlar, Metastatic Melanoma, BRAF V600E Mutation

Med-Chemist ― 3 hr 21 min ago

FDA Approves Revlimid (lenalidomide) for the Treatment of Patients with Relapsed or Refractory Mantle Cell Lymphoma

FDA Approves Revlimid (lenalidomide) for the Treatment of Patients with Relapsed or Refractory Mantle Cell Lymphoma

Med-Chemist ― In continuation of my update on Lenalidomide ∙ We know that, Lenalidomide (Revlimid) is a derivative of thalidomide introduced in 2004. It was initially intended as a treatment for multiple myeloma, for which thalidomide is an accepted...

Tags: Thalidomide, Lenalidomide (Revlimid), Relapsed Or Refractory Mantle Cell Lymphoma, FDA Approval

Med-Chemist ― 3 hr 21 min ago

Diabetes drug points the way to overcoming drug resistance in melanoma

Med-Chemist ― Despite success with BRAFV600E inhibitors, therapeutic responses in patients with metastatic melanoma are short-lived because of the acquisition of drug resistance. Researchers identified a mechanism of intrinsic multidrug resistance based on the...

Tags: H3K4-demethylase JARID1B/KDM5B/PLU-1, BRAFV600E Inhibitors, Cisplatin And Vemurafenib, JARID1Bhigh

Med-Chemist ― 3 hr 21 min ago

Bristol-Myers Squibb Receives US FDA sNDA Approval for Use of SUSTIVA® (efavirenz) in HIV-1 Infected Pediatric Patients | BMS Newsroom

Bristol-Myers Squibb Receives US FDA sNDA Approval for Use of SUSTIVA® (efavirenz) in HIV-1 Infected Pediatric Patients | BMS Newsroom

Med-Chemist ― We know that, Efavirenz (EFV, brand names Sustiva, Stocrin, Efavir etc.) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) and is used as part of highly active antiretroviral therapy (HAART) for the treatment of a human immunodeficiency...

Tags: Highly Active Antiretroviral Therapy (HAART), Stocrin, Brand Names Sustiva, Non-nucleoside Reverse Transcriptase Inhibitor (NNRTI), Efavir Etc.), Efavirenz (EFV

Med-Chemist ― 3 hr 21 min ago

Flamel Technologies Announces FDA Approval of Bloxiverz

Med-Chemist ― Flamel Technologies today announced that the U.S. Food and Drug Administration (FDA) has approved the company's New Drug Application (NDA) for Bloxiverz (neostigmine (see structure below) methylsulfate), a drug used intravenously in the operating...

Tags: Bloxiverz (neostigmine Methylsulfate), FDA Approval

Med-Chemist ― 3 hr 21 min ago

FDA Approves TOBI Podhaler

FDA Approves TOBI Podhaler

Med-Chemist ― We know that, Tobramycin is an aminoglycoside antibiotic derived from Streptomyces tenebrarius and used to treat various types of bacteria infections, particularly Gram-negative infections. It is especially effective against species of ...

Tags: Streptomyces Tenebrarius, Pseudomonas., Tobramycin Is An Aminoglycoside Antibiotic

Med-Chemist ― 3 hr 21 min ago

Diabetes drug shows promise in treatment of neurodegenerative disease

Med-Chemist ― In continuation of my update on Pioglitazone ∙ We know that, Pioglitazone is a prescription drug of the class thiazolidinedione (TZD) with hypoglycemic (antihyperglycemic, antidiabetic) action to treat diabetes. It is used to improve ...

Tags: Type II Diabetes, Thiazolidinedione (TZD), Pioglitazone, Neurodegenerative Disease

Med-Chemist ― 3 hr 21 min ago

FDA Approves Mekinist (trametinib) for Advanced Melanoma

FDA Approves Mekinist (trametinib) for Advanced Melanoma

Med-Chemist ― In continuation of my update on Trametinib ∙ GlaxoSmithKline plc announced today that the U.S. Food and Drug Administration (FDA) has approved Mekinist (trametinib) as a single-agent oral treatment for unresectable or metastatic melanoma ...

Tags: Advanced Melanoma, Mekinist, Trametinib, BRAF V600E Or V600K Mutations

Med-Chemist ― 1 week 5 days ago

Cancer Fighting Foods.............

Cancer Fighting Foods.............

Med-Chemist ― Cancer Fighting Foods: ∙ How can food fight cancer, you ask? In many, many ways! Certain healthy foods can lower your risk for cancer by repairing damaged cells and protect sensitive skin. Incorporating more plant-based foods into your diet ...

Med-Chemist ― 1 week 6 days ago

Raptor Pharmaceutical's PROCYSBI™ Receives FDA Approval for the Treatment of Nephropathic Cystinosis

Raptor Pharmaceutical's PROCYSBI™ Receives FDA Approval for the Treatment of Nephropathic Cystinosis

Med-Chemist ― Cysteamine bitartrate, is a cystine depleting agent which lowers the cystine content of cells in patients with cystinosis, an inherited defect of lysosomal transport. It is an aminothiol, beta-mercaptoethylamine. Cysteamine bitartrate is a...

Tags: Procysbi, Nephropathic Cystinosis, Cysteamine Bitartrate

Med-Chemist ― 2 weeks 1 day ago

Arbor Pharmaceuticals Announces FDA Approval of Nymalize

Arbor Pharmaceuticals Announces FDA Approval of Nymalize

Med-Chemist ― We know that, Nimodipine (marketed by Bayer as Nimotop) is a dihydropyridine calcium channel blocker originally developed for the treatment of high blood pressure. It is not frequently used for this indication, but has shown good results in...

Tags: Dihydropyridine Calcium Channel Blocker, High Blood Pressure, Subarachnoid Hemorrhage (SAH)., Nimotop, Nimodipine

Med-Chemist ― 2 weeks 2 days ago

Research aims for insecticide that targets malaria mosquitoes

Med-Chemist ― Acetylcholinesterase helps regulate nervous system activity by stopping electrical signaling in nerve cells. If the enzyme can't do its job, the mosquito begins convulsing and dies. The research team's goal is to develop compounds perfectly...

Tags: Antimalarial, Drug Discovery, Drugs, Acetylcholinesterase, Tubocurarine

Med-Chemist ― 2 weeks 4 days ago

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